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本文旨在通过光镜研究骨关节炎的颞下颌关节中滑膜的特征,以评估滑膜在骨关节炎进展过程中的作用。 作者对40例长期接受非外科治疗的难治性颞下颌关节病患者(女33例,男7例,平均29.4岁)以关节镜取单侧关节上腔滑膜活检。经固定、包埋、切片后以甲苯胺蓝染色。其种31例被诊断为有骨关节炎,定为骨关节炎组,组内又再根据有无关节盘移位和穿孔引起的症状分为:无关节盘累及组(ADI组,6例)、可复位的关节盘移位组(RDD组,0例)、关节盘移位组(PDD组,22例)、关节盘穿孔组(DP组,3例)。另外9例患者无骨关节炎,定为对照组,组内又分为疼痛性移位过度(6例)、创伤性关节炎(2例)、疼痛性过载荷(1例)3组。 光镜观察结果发现骨关节病组滑膜内膜细胞层数显著多于对照组,纤维内膜基质及内膜下纤维化也显
The aim of this paper is to characterize the synovial membrane of the temporomandibular joint of osteoarthritis by light microscopy to assess the role of the synovium in the progression of osteoarthritis. The authors of 40 patients with long-term non-surgical treatment of refractory temporomandibular joint disease patients (33 males and 7 females, mean 29.4 years) to take unilateral arthroscopic synovial biopsy. Fixed, embedded, sliced with toluidine blue staining. The 31 cases were diagnosed as having osteoarthritis, which were classified as osteoarthritis group. The patients were divided into the following groups according to the presence or absence of dislocation and perforation. There were 6 cases without ADH (ADI group) (RDD group, n = 0), disc displacement group (PDD group, n = 22) and perforation group (n = 3). The other 9 patients were free of osteoarthritis. The patients were divided into control group (6 cases), traumatic arthritis (2 cases) and pain overload (1 case). Light microscope observation found that the number of synovial intima cell layers in the group of osteoarthropathy was significantly more than that in the control group, and the fibrous endometrium and subintimal fibrosis were also significantly