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目的:探讨急诊血液灌流联合血液透析在抢救重度乌头碱中毒的价值。方法:选取2014年1月至2015年12月我院收治的重度乌头碱中毒的患者32例,并随机分为对照组和实验组各16例,对照组在早期彻底洗胃、抗心律失常等治疗方法的基础上应用血液灌流手段进行血液灌流治疗,实验组在对照组的基础上联合血液透析治疗;比较两组的临床疗效。结果:实验组中痊愈13例,显效、有效和无效各1例,总有效率为93.8%(15/16);对照组中痊愈8例,显效、有效各1例,无效6例,总有效率为62.5%(10/16)。实验组的总有效率明显高于对照组(P<0.05)。结论:在常规治疗的基础上,血液灌流联合血液透析在抢救重度乌头碱中毒中能有效纠正患者的心律失常,提高治愈率,降低死亡率,值得在临床上推广应用。
Objective: To investigate the value of emergency hemoperfusion combined with hemodialysis in the rescue of severe aconitine poisoning. Methods: Thirty-two patients with severe aconitine poisoning in our hospital from January 2014 to December 2015 were selected and randomly divided into control group and experimental group of 16 cases. In the control group, gastric lavage and antiarrhythmic And other treatment methods based on the use of hemoperfusion means of hemoperfusion treatment, the experimental group in the control group based on hemodialysis treatment; the clinical efficacy of the two groups were compared. Results: In the experimental group, 13 cases were cured, 1 case markedly effective, effective and ineffective, the total effective rate was 93.8% (15/16); in the control group, 8 cases were cured, 1 case markedly effective, 1 case ineffective, 6 cases ineffective, The efficiency is 62.5% (10/16). The total effective rate of experimental group was significantly higher than that of control group (P <0.05). Conclusion: On the basis of routine treatment, hemoperfusion combined with hemodialysis can effectively correct arrhythmia in patients with severe aconitine poisoning, improve cure rate and reduce mortality, which is worth popularizing in clinic.