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目的探讨常规全身抗结核治疗联合利福平经纤支镜注射介入治疗支气管结核的疗效。方法对80例支气管结核分别行纤维支气管镜注入利福平注射液,异烟肼+阿米卡星,单纯口服抗结核药物3组治疗结果进行对比分析。结果经纤支镜注射利福平介入治疗支气管结核,较纤维支气管镜注入异烟肼+阿米卡星和单纯口服抗结核药物有显著差异。结论通过纤维支气管镜于病灶处注入利福平注射液治疗支气管结核起效快、效果佳、不良反应少,对减少支气管狭窄、肺不张、毁损肺的发生,提高患者的生存质量有积极的意义。
Objective To investigate the efficacy of conventional systemic antituberculous therapy combined with rifampicin via bronchofibroscopy in the treatment of bronchial tuberculosis. Methods Eighty cases of bronchial tuberculosis were treated with bronchoscopy with rifampin injection, isoniazid + amikacin, oral administration of anti-tuberculosis drugs in three groups were compared. Results The treatment of bronchial tuberculosis by bronchoscopy with rifampicin was significantly different from that of bronchial injections of isoniazid + amikacin and oral anti-tuberculosis drugs alone. Conclusions The injection of rifampicin in the lesion by fiberoptic bronchoscopy is rapid and effective in treating bronchial tuberculosis and has few adverse reactions. It has a positive effect on reducing the occurrence of bronchial stenosis, atelectasis, destroying the lung and improving the quality of life of patients significance.