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目的 观察康泉 (化学名盐酸格拉司琼 )控制肿瘤患者化疗引起的胃肠道反应的疗效。方法 10 0例随机分为两组 ,6 0例采用康泉治疗 ,40例采用胃复安加吗丁啉治疗 (对照组 ) ,并对两组的有效率进行比较。结果 康泉组控制恶心有效率为 71.7% ,对照组为 42 .5 % ,两组比较有明显差异 (p<0 .0 1) ;康泉组控制化疗所致呕吐有效率为 80 .0 % ,对照组为45 .0 % ,两组比较有明显差异 (p<0 .0 1)。结论 康泉能有效控制化疗引起的胃肠道反应。
Objective To observe the efficacy of Kangquan (chemical name granisetron hydrochloride) in the control of chemotherapy-induced gastrointestinal reactions in cancer patients. Methods 100 cases were randomly divided into two groups, 60 cases were treated with Kangquan, 40 cases were treated with metoclopramide plus gadobutrolide (control group), and the efficacy of the two groups was compared. Results The effective rate of control of nausea in the Kangquan group was 71.7% and 42.5% in the control group. There was a significant difference between the two groups (p<0.01). The effective rate of vomiting caused by chemotherapy-controlled Kangquan group was 80.0 %. The control group was 45.0%. There was a significant difference between the two groups (p<0.01). Conclusion Kangquan can effectively control the gastrointestinal reactions induced by chemotherapy.