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目的:探讨清开灵注射液联合阿奇霉素对小儿支原体肺炎患者血清T-IgE和ECP影响。方法:选取我院收治的支原体肺炎患儿50例,随机分为实验组和对照组。两组均予阿奇霉素对症治疗,实验组在此基础上加用清开灵注射液治疗。观察并比较两组患儿治疗前后血常规各指标变化情况以及T-IgE、ECP水平的变化。结果:与治疗前相比,两组患者治疗后中性粒细胞比例降低,淋巴细胞比例升高,单核细胞比例降低(P<0.05),且实验组治疗组中性粒细胞比例较对照组更低,淋巴细胞比例较高,单核细胞比例较低(P<0.05)。治疗后3、7、14天,两组患儿的血清T-IgE及ECP水平呈下降趋势,与前一时间点比较,两组患者的T-IgE及ECP水平均较低(P<0.05),与对照组比较,实验组同意时间点T-IgE及ECP水平较低(P<0.05)。结论:清开灵注射液联合阿奇霉素能够明显降低小儿支原体肺炎患儿血清T-IgE和ECP水平。
Objective: To investigate the effect of Qingkailing injection combined with azithromycin on serum T-IgE and ECP in children with mycoplasmal pneumonia. Methods: Fifty children with Mycoplasma pneumonia admitted in our hospital were randomly divided into experimental group and control group. Both groups were given azithromycin symptomatic treatment, experimental group on the basis of Qingkailing injection. The change of blood routine indexes and the changes of T-IgE and ECP levels in both groups were observed and compared before and after treatment. Results: Compared with those before treatment, the proportion of neutrophils decreased, the proportion of lymphocytes increased, the percentage of monocytes decreased in both groups (P <0.05), and the ratio of neutrophils in experimental group was higher than that in control group Lower, higher proportion of lymphocytes and lower proportion of monocytes (P <0.05). The levels of T-IgE and ECP in both groups showed a decreasing trend on the 3rd, 7th and 14th day after treatment. T-IgE and ECP levels in both groups were lower than those in the previous time point (P <0.05) Compared with the control group, the experimental group agreed that the levels of T-IgE and ECP at the time points were lower (P <0.05). Conclusion: Qingkailing injection combined with azithromycin can significantly reduce children with mycoplasma pneumonia in children with serum T-IgE and ECP levels.