猝死是冠心病(CHD)的一个显著的、致命的特征,业已认识,CHD患者中猝死的危险性为同年龄的普通人群的若干倍.作者报告Framingham研究参与者在30年观察期间CHD的猝死率.调查对象为30～62岁的成人5209例.他们具有城镇成人样本的代表性,每2年随访一次,并观察新近发生的包括猝死的临床症状.新近出现的冠心病事件,包括心绞痛、冠状动脉供血不全综合征——心肌梗塞和冠心病死亡(包括猝死).象其他数分钟内死亡的疾病一样,归因于冠心病的猝死主要是根据推论而作出的.如能排除主动脉夹层动脉瘤、动脉瘤破裂、肺栓塞,则提示其发生与冠心病有关.这是Framingham研究采用的定义,而不是WHO创导的非特异性24小时定义.将出现CHD症状存活者列为处于危险状态组,并与无症状的同年龄者比较,从而评定危险因子 Sudden death is a significant and fatal feature of coronary heart disease (CHD), and it has been recognized that the risk of sudden death in CHD patients is several times higher than that of the general population of the same age. The authors report that participants in the Framingham study had been associated with sudden death of CHD during 30 years of observation Rate The subjects were 5209 adults aged 30 to 62. They were representative of urban adult samples and were followed up every 2 years and observed for newly occurring clinical symptoms including sudden death.Nearly recent events of coronary heart disease including angina pectoris, Coronary insufficiency syndrome - death from myocardial infarction and coronary heart disease (including sudden death) Like other diseases that die within a few minutes, sudden death due to coronary heart disease is mainly based on inference and exclusion of aortic dissection Aneurysms, ruptured aneurysms, and pulmonary embolism suggest a relationship with coronary heart disease, a definition used in the Framingham study rather than a non-specific 24-hour definition by WHO. Survivors with CHD symptoms were classified as at risk Group and compared with asymptomatic persons of the same age to assess risk factors