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目的：探讨急性非淋巴细胞白血病（ＡＮＬＬ）早期病死的危险因素。方法：ＡＮＬＬ３０１例分Ａ组（早期病死组）９７例，Ｂ组（非早期病死组）２２２例，对１２项指标进行单因素分析，筛选早期病死的可能危险因素，再行Ｌｏｇｉｓｔｉｃ回归分析，寻找危险因素。结果：单因素分析时脾大、高热、白细胞、血小板、增生度、白血病类型、骨髓原始加（早）幼细胞等７个指标，Ａ、Ｂ两组差别具有统计学意义；Ｌｏｇｉｔｉｃ回归分析时，白细胞≥１００×１０９／Ｌ、增生极度活跃、高热≥３９℃、血小板≤２０×１０９／Ｌ及白血病类型（Ｍ５）等指标进入回归方程，其相对危险度分别为５．０２１６，４．８７４４，３．３３０２，３．２０４８和２．１６７７。结论：早期病死的危险因素按相对危险度由大到小排列如下，白细胞≥１００×１０９／Ｌ、骨髓增生极度活跃、高热（≥３９℃）、血小板≤２０×１０９／Ｌ和白血病类型。
Objective: To investigate the risk factors of early non-lymphocytic leukemia (ANLL) death. METHODS: A total of 301 cases of ANLL were divided into group A (early death group) in 97 cases and group B (non-early stage death group) in 222 cases. The univariate analysis was performed on 12 factors and the possible risk factors for early death were screened. Logistic regression analysis was performed again to find Risk factors. Results: There were 7 indicators such as splenomegaly, hyperthermia, leukocyte, platelet, hyperplasia, leukemia type, and bone marrow primordial plus (premature) pups in the univariate analysis. There was a statistically significant difference between group A and B. Logitic regression analysis was used. Leukocyte ≥100×109/L, hyperplasia hyperactive, hyperthermia ≥39°C, platelet ≤20×109/L and leukemia type (M5) and other indicators entered the regression equation, the relative risk was 5.0216,4.8744, respectively. 3.3302, 3.2048, and 2.1677. Conclusions: The risk factors for early mortality are ranked as follows from the greatest to the lowest risk: white blood cells ≥100×109/L, myeloproliferative hyperactivity, hyperthermia (≥39°C), platelet ≤20×109/L, and leukemia types.