随着多种应激因素的加剧,抑郁症已成为现代社会的常见病,严重危害着人类的身心健康。近年来,随着对抑郁症病理生理改变认识的逐步深入,抗抑郁药作用机制的研究也取得了一些进展。传统的单胺递质理论和受体理论已不能充分解释抗抑郁药的临床效应滞后现象,而一些新的作用机制则越 With the exacerbation of various stress factors, depression has become a common disease in modern society, seriously endangering the physical and mental health of human beings. In recent years, with the deepening of the understanding of the pathophysiological changes of depression, some progress has been made in the study of the mechanism of action of antidepressants. Traditional monoamine neurotransmitter theory and receptor theory can not fully explain the clinical effects of antidepressants lag phenomenon, and some of the new mechanism of action is the more