1877年Ehrlich用硷性染料染色,发现在结缔组织中存在一种含有异染性颗粒的细胞称为肥大细胞.它的主要作用是保护组织不受损伤和刺激,在许多疾病中肥大细胞也参与了重要的病理过程.随着研究的进一步深入,肥大细胞越来越为人们所重视.现仅就肥大细胞的形态、生理、生化特性和一些皮肤、粘膜疾病中肥大细胞的变化综述如 In 1877 Ehrlich stained with a basic dye and found that in the connective tissue there is a cell containing heterochromatic particles called mast cells and its main role is to protect the tissue from damage and stimulation in many diseases mast cells are also involved An important pathological process.With further research, more and more attention to mast cells.Considering the morphological, physiological, biochemical characteristics of mast cells and some changes in mast cells in mucosal diseases, such as