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目的观察自体角膜缘干细胞移植术治疗翼状胬肉的临床疗效。方法采用自体角膜缘干细胞移植术对30例(30眼)翼状胬肉患者进行治疗,术后随访6个月到2年。结果术后均有轻度流泪或异物感,于角膜上皮修复后上述症状消失,角膜上皮缺损多在术后3~4d愈合。术后观察6~24个月,有28眼治愈,治愈率93.3%,有2例复发,占总数的6.7%。结论自体角膜缘干细胞移植,具有操作简单、取材方便等优点,并且可以显著降低翼状胬肉的复发率,是治疗翼状胬肉较为理想的方法。
Objective To observe the clinical efficacy of autologous limbal stem cell transplantation in the treatment of pterygium. Methods Thirty patients (30 eyes) with pterygium were treated with limbal stem cell transplantation. The patients were followed up for 6 months to 2 years. Results Postoperative mild tears or foreign body sensation, the above symptoms disappeared after corneal epithelial repair, corneal epithelial defects were mostly healed after 3 ~ 4d. Postoperative observation of 6 to 24 months, 28 eyes were cured, the cure rate was 93.3%, 2 cases of recurrence, accounting for 6.7% of the total. Conclusion Autologous limbal stem cell transplantation has the advantages of simple operation, convenient drawing, and can significantly reduce the recurrence rate of pterygium, which is an ideal method for the treatment of pterygium.