近来,发现在塞内加尔北部地区用标准剂量的吡喹酮治疗曼氏血吸虫病的治愈率很低(18％—36％),为了解出现上述情况有无相关的宿主因素,作者针对年龄、性别、感染度、有无吡喹酮治疗史、个体疫水接触习惯及特异性抗体水平进行了如下研究。 自1991年8月至1993年9月期间,在塞内加尔曼氏血吸虫病疫区,每隔8个月随机选择4组人群(组1—4),每组400人,收 Recently, it was found that the treatment rate of manchurian schistosomiasis with the standard dose of praziquantel in the northern part of Senegal was very low (18% -36%). To find out whether there was any relevant host factor in the above situation, the authors investigated the effects of age, gender, The degree of infection, the history of praziquantel treatment, the contact habits of the individual’s poliovirus and the level of the specific antibody were studied as follows. From August 1991 to September 1993, four groups of patients (Groups 1-4) were randomly selected at intervals of 8 months in the Sentinel Schistosoma mansoni area, each containing 400 persons