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目的分析和探讨乙型肝炎(乙肝)肝硬化并发原发性肝癌的相关危险因素。方法 120例乙肝肝硬化患者作为研究对象,分析乙肝肝硬化并发原发性肝癌的危险因素。结果性别、肝癌家族史、糖尿病、长期吸烟史、其他肿瘤家族史、抗病毒治疗以及HBV DNA水平都会影响乙肝肝硬化并发原发性肝癌的发生,其中,糖尿病、长期吸烟史、未予以抗病毒治疗以及HBV DNA阳性为独立危险因素。结论对于糖尿病、长期吸烟史、未予以抗病毒治疗以及HBV DNA阳性的乙肝肝硬化患者,在临床上应予以注意和预防,以防止原发性肝癌的发生。
Objective To analyze and explore the relevant risk factors of hepatitis B (hepatitis B) cirrhosis complicated with primary liver cancer. Methods A total of 120 patients with hepatitis B cirrhosis were enrolled in this study. The risk factors of hepatitis B cirrhosis complicated with primary liver cancer were analyzed. Results Sex, family history of HCC, diabetes mellitus, long-term smoking history, family history of other tumors, antiviral therapy and HBV DNA level all affect the occurrence of hepatocellular carcinoma of liver cirrhosis complicated with primary liver cancer. Among them, diabetes, long-term smoking history, Treatment and HBV DNA positive are independent risk factors. Conclusion In patients with hepatitis B cirrhosis who have not been treated with antiviral therapy and have a history of diabetes, long-term smoking, HBV DNA should be taken precaution and prevention in order to prevent the occurrence of primary liver cancer.