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用ELISA法检测52例急性肝炎(简称急肝),38例慢性迁延性肝炎(简称慢迁肝)及45例慢性活动性肝炎(简称慢活肝)血清中抗-HBc和IgM抗-HBc的水平,同时用RIA法检测HBsAg。结果表明,IgM抗-HBc在急肝和慢活肝中阳性率高,在慢迁肝中阳性率低,统计学上差异显著;平均几何滴度,各组间无显著性差异。抗-HBc滴度以慢活肝最高,与慢迁肝和急肝比较有极显著性差异。在急肝中,抗-HBc显著升高或IgM抗-HBc持续阳性者,其HBsAg不易转阴。并对抗-HBc滴度与HBsAg阳性的关系进行讨论。
The serum levels of anti-HBc and IgM anti-HBc in serum of 52 cases of acute hepatitis (referred to as acute liver), 38 cases of chronic persistent hepatitis (abbreviated as slow-moving liver) and 45 cases of chronic active hepatitis Level, at the same time using RIA method to detect HBsAg. The results showed that the positive rate of anti-HBc IgM in acute and chronic liver was high, and the positive rate in slow-moving liver was low with statistically significant difference. The average geometric titers were not significantly different among groups. Anti-HBc titer to slow the highest living liver, and slowly moving liver and acute liver more significant differences. In the acute liver, anti-HBc significantly increased or IgM anti-HBc persistent positive, its HBsAg is not easy to negative. The relationship between anti-HBc titer and HBsAg positivity was also discussed.