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目的探讨胆石症的形成与垂体肾上腺、甲状腺激素的关系。方法借助放射免疫方法测定了32例(男9例,女23例)胆石症患者血清 ACTH,Cor,TSH,T_3,T_4的含量,并与32例健康献血员对照分析。结果胆结石患者的 Cor 水平与对照组比较(4.54±2.84,3.62±1.06μmol/L,P<0.05)明显升高。T_3水平(0.85±0.35,17.25±0.35pmol/L,P<0.01)明显下降,而ACTH,TSH,T_4无变化。结论胆结石的形成与血清 Cor水平升高,T_3水平降低有关。
Objective To investigate the relationship between cholelithiasis and pituitary adrenal gland and thyroid hormone. Methods Serum levels of ACTH, Cor, TSH, T_3 and T_4 in 32 patients (9 males and 23 females) were determined by radioimmunoassay and compared with 32 healthy blood donors. Results The level of Cor in gallstone patients was significantly higher than that in the control group (4.54 ± 2.84, 3.62 ± 1.06μmol / L, P <0.05). T_3 levels (0.85 ± 0.35,17.25 ± 0.35pmol / L, P <0.01) decreased significantly, while ACTH, TSH, T_4 had no change. Conclusion The formation of gallstones is associated with the increase of serum Cor level and T_3 level.