家蝇酚氧化酶原系统是家蝇免疫体系重要的组成部分,在对病原识别和免疫防御中发挥着强有力的作用。目前,对该系统的关键基因和作用机制还不清楚。为此,进行了家蝇转录组分析,得到参与酚氧化酶原系统的酚氧化酶原、酚氧化酶原激活酶、Serpin型丝氨酸蛋白酶抑制因子及上游的模式识别受体等关键基因的EST(基因表达序列标签),现就它们的研究进展予以综述。 The housefly phenoloxidase system is an important part of housefly immune system and plays a powerful role in pathogen identification and immune defense. At present, the key genes and mechanism of action of this system are not yet clear. For this purpose, transcriptomic analysis of Musca domestica was carried out to obtain the ESTs of key genes such as phenoloxidase, phenoloxidase, properoxenase, Serpin type serine protease inhibitors and upstream pattern recognition receptors involved in the phenoloxidase system Gene expression sequence tags), are reviewed on their research progress.