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依布硒啉为化学合成的一种有机硒化合物,(2-phenyl-1,2-benzoisosenazol-3(2H)-one),是一种新型非甾体抗炎药。有研究表明,该药具有谷胱甘肽过氧化酶样作用,有抗高压氧效应,对中枢神经系统氧毒性有防治作用。本文选用多种炎症模型观察了依布硒啉的抗炎作用。
Ebselen, a kind of organic selenium compound synthesized chemically, is a new non-steroidal anti-inflammatory drug. Studies have shown that the drug has glutathione peroxidase-like effect, anti-hyperbaric oxygen effect on the central nervous system oxygen toxicity prevention and treatment. This article selected a variety of inflammatory models observed Ebselen anti-inflammatory effect.