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目的对24例粒细胞缺乏症进行分析,为诊治该病提供临床参考。方法2006年1月～12月住院患儿中粒细胞缺乏症24例,对其临床资料、实验室检查结果及治疗转归进行分析总结。结果24例中<1岁占54%,1-3岁占25%,>3岁占21%;其中呼吸道感染占71%,以急性上呼吸道感染多见。本组10例患儿伴贫血,2例血小板下降,3例全血细胞减少。平均住院日(5.7±2.3)d。结论粒细胞缺乏症在儿科临床中并不少见,其临床意义主要提示感染,病程多呈良性经过;对伴贫血和(或)血小板减少的患儿,必要时行骨髓穿刺检查,以排除少见疾病。
Objective To analyze 24 cases of agranulocytosis and provide clinical reference for the diagnosis and treatment of this disease. Methods From January 2006 to December 2006, 24 cases of neutrophil in hospitalized children were analyzed. The clinical data, laboratory test results and treatment outcome were analyzed and summarized. Results Of the 24 cases, <1 year old accounted for 54%, 1-3 years old 25%, and> 3 years old 21%. Among them, 71% of them were respiratory infections, most of which were acute upper respiratory tract infections. The group of 10 children with anemia, 2 cases of platelet decline, 3 cases of pancytopenia. The average length of stay (5.7 ± 2.3) d. Conclusions Gliosis is not uncommon in pediatric clinical practice, and its clinical significance mainly indicates infection. The course of the disease is mostly benign. In patients with anemia and / or thrombocytopenia, if necessary, bone marrow biopsy should be performed to exclude rare diseases .