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川芎嗪(TMP-四甲基吡嗪)是中草药川芎的提取物,其化学合成的盐酸川芎嗪注射液已广泛在中国应用于临床心脑血管病的治疗。然而,其效应的分子机理还不清楚。本研究目的是测定TMP是否和怎样影响白细胞对ICAM-1的粘附。材料和方法做吸管技术被用于测量单细胞对(由一个白细胞
Ligustrazine (TMP-tetramethylpyrazine) is an extract of the Chinese herbal medicine Chuanxiong. Its chemically synthesized ligustrazine hydrochloride injection has been widely used in the treatment of clinical cardiovascular and cerebrovascular diseases in China. However, the molecular mechanism of its effect is not yet clear. The purpose of this study was to determine whether and how TMP affects leukocyte adhesion to ICAM-1. Materials and Methods Pipette Technology Used to Measure Single Cell Pairs (by One White Cell