在家兔中使用自体血凝块可以引起实验性栓塞性中风。在中风发生后1小时,对其施行肝素抗凝治疗,观察到在短期(5小时)内接受超量肝素的家兔,其凝血激酶时间是未接受肝素者的3倍;而只接受适量肝素者,则其凝血激酶时间为未接受肝素者的1.2～2.5倍。处死动物后进行解剖,发现有肉眼可见的脑内出血证据。但经肝素抗凝治疗的家兔与未经治疗家兔相比。脑内出血没有明显的增加。上述资料表 The use of autologous blood clots in rabbits can cause experimental embolic stroke. At 1 hour after the stroke, heparin anticoagulation was performed and rabbits receiving an overdose of heparin within a short period of time (5 hours) were found to have 3 times as much thromboplastin time as those who did not receive heparin, whereas only moderate heparin , Then the thromboplastin time was 1.2 to 2.5 times those who did not receive heparin. The animals were sacrificed and dissected to find evidence of gross intracerebral hemorrhage. However, the heparin anticoagulant treatment of rabbits compared with untreated rabbits. No significant increase in intracerebral hemorrhage. The above information sheet