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目的分析新生儿念珠菌感染的发病原因、临床特点、易感因素及治疗效果,预防新生儿医院内感染发生。方法对2005年1月至2010年1月收治的97例新生儿念珠菌感染患儿的临床资料作回顾性分析。结果 2860例住院新生儿发生新生儿念珠菌感染97例,发生率为3.39%。发病高危因素为早产、低体质量、严重细菌感染、免疫功能低下及长期使用抗生素。常见的临床表现为哭闹、吃奶量减少、口腔唇舌和颊黏膜局部呈潮红斑片状,表面覆以大小不等乳白色块状物,较易剥离。结论念珠菌感染是医院感染的常见致病菌,易造成流行,应引起高度重视。
Objective To analyze the etiological factor, clinical features, susceptibility factors and therapeutic effect of neonatal Candida infection and to prevent the occurrence of nosocomial infections in neonates. Methods The clinical data of 97 neonates with Candida infection in neonates admitted from January 2005 to January 2010 were analyzed retrospectively. Results A total of 97 cases of neonatal Candida infections occurred in 2860 hospitalized newborns, the incidence was 3.39%. Risk factors for the onset of preterm birth, low body mass, severe bacterial infection, immunocompromised and long-term use of antibiotics. Common clinical manifestations of crying, reduce the amount of milk, oral lip and buccal mucosa was partial erythema patchy surface covered with different sizes of milk white lumps, easier to peel. Conclusions Candida infection is a common pathogen of nosocomial infection and can easily lead to epidemic. It should be given high priority.