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α-羟基膦酸及其酯具有广泛的生物活性,详细介绍了使用手性辅助基团诱导和手性催化剂催化等方法合成光学活性α-羟基膦酸(酯)的研究进展.
α-Hydroxyphosphonic acid and its esters have a wide range of biological activities. The progress in the synthesis of optically active α-hydroxyphosphonic acid esters using chiral auxiliary groups and catalysis of chiral catalysts is described in detail.