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目前广泛应用凝胶沉淀反应或放射免疫分析检测患者血清或腹水的甲胎蛋白含量,以诊断原发性肝细胞性癌。但在血清或腹水中往往并不都能反应出肝癌细胞实际所合成的甲胎蛋白值。 Watabe和Hirai等以沉淀反应检测了78株腹水肝癌细胞所致肝癌鼠的血清和腹水中的甲胎蛋白值。他们发现其中有26株细胞能合成不同浓度的甲胎蛋白,余52株未检出甲胎蛋
At present, the use of gel precipitation reaction or radioimmunoassay to detect the level of alpha-fetoprotein in the serum or ascites of patients to diagnose primary hepatocellular carcinoma. However, in the serum or ascites, it is not always possible to reflect the actual synthesis of alpha-fetoprotein in liver cancer cells. Watabe and Hirai et al. detected alpha-fetoprotein (AFP) levels in the serum and ascitic fluid of hepatocarcinoma-induced liver cancer cells in 78 ascites liver cancer cells using a precipitation reaction. They found that 26 of them could synthesize alpha-fetoprotein at different concentrations, and 52 of them had not detected alpha fetal eggs.