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目的探讨奥卡西平治疗原发性三叉神经痛的疗效及对睡眠质量的影响。方法采用随机平行对照法将我院收治的81例原发性三叉神经痛患者进行分组,对照组40例患者采用卡马西平治疗,观察组41例患者采用奥卡西平治疗。比较两组患者治疗后的临床疗效及治疗前后匹茨堡睡眠质量指数量表评分(PSQI)。结果观察组治疗后临床总有效率95.12%明显高于对照组80.00%,具有统计学意义(P<0.05)。治疗后两组患者PSQI均有所下降,但观察组治疗后PSQI明显低于对照组,具有统计学意义(P<0.05)。结论采用奥卡西平治疗原发性三叉神经痛能够改善患者的睡眠质量及预后,提高临床总有效率,降低PSQI,值得临床推广使用。
Objective To investigate the curative effect of oxcarbazepine on primary trigeminal neuralgia and its effect on sleep quality. Methods Eighty-one patients with primary trigeminal neuralgia admitted to our hospital were divided into two groups according to randomized parallel control. Forty patients in the control group were treated with carbamazepine. Forty-one patients in the observation group were treated with oxcarbazepine. The clinical efficacy and the Pittsburgh Sleep Quality Index Scale (PSQI) before and after treatment were compared between the two groups. Results After treatment, the total clinical effective rate was 95.12% in the observation group, which was significantly higher than that in the control group (80.00%, P <0.05). PSQI decreased in both groups after treatment, but the PSQI in the observation group was significantly lower than that in the control group (P <0.05). Conclusion The treatment of primary trigeminal neuralgia with oxcarbazepine can improve the quality of sleep and prognosis of patients, improve the total effective rate and reduce the PSQI, which is worthy of clinical promotion.