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目的:观察超微玉屏风丸对肿瘤患者化疗后白细胞减少症及细胞免疫功能的影响,并探讨其作用机制。方法:按照随机对照原则,将患者分为治疗组和对照组,以量化评分标准为手段,观察患者外周血中白细胞计数、中医症候疗效、生活质量及T细胞亚群等指标的变化。结果:与对照组比较,治疗组白细胞计数明显增加(P<0.05);患者临床症状改善,生活质量提高(P<0.05或P<0.01);T淋巴细胞比例均明显提高(P<0.05或P<0.01)。结论:超微玉屏风丸能明显改善白细胞减少症患者的临床症状,上调外周血白细胞水平,增强患者的免疫功能。
Objective: To observe the effect of Chaoyu Yupingfeng pill on leukopenia and cellular immune function after chemotherapy in cancer patients and to explore its mechanism. Methods: According to the randomized control principle, the patients were divided into treatment group and control group. Quantitative criteria were used as a measure to observe the changes of peripheral blood white blood cell count, TCM symptoms, quality of life and T cell subsets. Results: Compared with the control group, the white blood cell count of the treatment group was significantly increased (P <0.05); the clinical symptoms were improved and the quality of life was improved (P <0.05 or P <0.01); the proportion of T lymphocytes was significantly increased (P <0.05 or P <0.01). Conclusion: Weijuanyuping pill can significantly improve the clinical symptoms of patients with leucopenia, raise the level of peripheral white blood cells and enhance the immune function of patients.