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目的观察曲美布汀联合复方消化酶治疗功能性消化不良的临床疗效。方法将113例功能性消化不良患者随机分为两组:曲美布汀联合复方消化酶治疗组(59例),吗叮啉对照组(56例),均连续用药4周,比较治疗后的临床症状积分和显效率及总有效率。结果治疗后两组患者症状积分治疗组明显优于对照组(P<0.05),临床疗效上治疗组、对照组显效率及总有效率分别为64.40%、93.22%和51.85%、83.33%,比较差异均有统计学意义(P<0.05)。结论曲美布汀联合复方消化酶治疗功能性消化不良的疗效显著优于单纯应用吗叮啉治疗。
Objective To observe the clinical efficacy of trimebutine combined with compound digestive enzymes in the treatment of functional dyspepsia. Methods 113 patients with functional dyspepsia were randomly divided into two groups: trimebutine combined with compound digestive enzyme treatment group (59 cases), morphinan control group (56 cases), were treated for 4 weeks, after treatment Clinical symptom score and markedly effective and total effective rate. Results After treatment, the symptom score of the two groups was significantly better than that of the control group (P <0.05). The clinical curative effect was 64.40%, 93.22% and 51.85%, 83.33% respectively in the treatment group and the control group The differences were statistically significant (P <0.05). Conclusion Trimebutine combined with compound digestive enzymes treatment of dysfunctional dyspepsia efficacy was significantly better than the simple application of treatment with dieldrin.