地方性克汀病是碘缺乏导致机体障碍谱带中最严重的表现之一。虽然典型的克汀病患者所占的比例很小,但由于患者的大脑、神经系统和体格发育受到了不可逆的损伤,从而给家庭和社会带来沉重的负担。该病被国内外学者广泛认可的主要原因是胚胎期和新生儿期严重缺碘所至,但仍 Local cretinism is one of the most serious manifestations of the body’s disordered spectrum caused by iodine deficiency. Although the typical proportion of patients with cretinism is small, it is a heavy burden on families and the community as a result of irreversible damage to the brain, nervous system and physical development of patients. The disease is widely recognized by scholars both at home and abroad mainly due to the severe iodine deficiency during the embryonic and neonatal periods. However,