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目的分析西安市2014年百日咳病例及实验室检测结果。方法对西安市2014年传染病报告系统中所报告的所有百日咳病例进行流行病学分析,并通过百日咳鲍特菌分离培养、鲍特菌属特异性PCR以及百日咳毒素Ig G检测方法对所有病例进行检测并分析。结果西安市2014年共报告百日咳病例71例,发病数较2013年(21例)增加238%,个别区县的发病率超过1/10万。3种实验方法显示共有41例为百日咳鲍特菌感染,6例为百日咳鲍特菌可疑感染,未见霍氏鲍特菌及副百日咳鲍特菌感染。其中PCR方法的检出率最高(90.2%)。结论百日咳发病可能有增高的趋势。尽快对报告病例进行实验室检测有助于百日咳病例的确诊。
Objective To analyze the 2014 cases of pertussis in Xi’an and laboratory test results. Methods Epidemiological analysis of all pertussis cases reported in the 2014 Infectious Disease Reporting System in Xi’an was carried out in all cases through the isolation and culture of Bordetella pertussis, the detection of Bordetella-specific PCR and Pertussis toxin Ig G Test and analyze. Results A total of 71 cases of whooping cough were reported in Xi’an in 2014, with a 238% increase in the number of cases compared with 2013 (21 cases). The incidence in individual districts and counties exceeded 1 in 10,000. Three kinds of experimental methods showed that there were 41 cases of Bordetella pertussis infection and 6 cases of pertussis pertussis suspicious infection, but there was no infection of Bordetella pertussis and Borrelia pertussis. PCR method which the highest detection rate (90.2%). Conclusion The incidence of pertussis may have increased trend. Laboratory testing of reported cases as soon as possible contributes to the diagnosis of whooping cough.