各种病因引起的慢性肝病及某些有毒物质所致的肝脏损伤，均可能具有肝细胞炎症、坏死，并继发纤维化的病理特征，是向肝硬化发展的中间环节。尽管肝纤维化尚未作为一个独立的疾病列入国际疾病分类学的范畴，但近年来随着医学分子生物技术的应用，人们对其发生的机制进行了广泛 A variety of causes of chronic liver disease and liver damage caused by certain toxic substances, may have hepatocellular inflammation, necrosis, and pathological features of secondary fibrosis, is an intermediate link to the development of cirrhosis. Although liver fibrosis has not been included in the International Classification of Diseases as an independent disease, in recent years, with the application of medical molecular biotechnology, the mechanism of its occurrence has been extensive