论文部分内容阅读
目的了解徐州市2006—2009年消灭脊髓灰质炎策略实施情况。方法收集2006—2009年报告的129例AFP病例的个案调查表和随访表,采集病例粪便标本、初免接种对象免前和免后血清标本和0岁~、1岁~、3岁~、5岁~、7岁~、15岁~、20岁~健康人群血清标本,分别进行病毒分离和抗体滴度检测。结果 129例AFP病例发病年龄最大的14岁,最小的83 d,男性71例,女性58例,分布于11个县(区),免疫次数≥4次的占77.5%。2006—20009年15岁以下儿童非脊灰AFP病例报告发病率分别为为2.33/10万、2.27/10万、1.92/10万和1.67/10万。Ⅰ、Ⅱ、Ⅲ型脊髓灰质炎疫苗基础免疫成功率分别为95.5%、94.0%、95.5%,Ⅰ、Ⅱ、Ⅲ型脊灰中和抗体阳性率分别为99.7%、98.3%、98.6%。结论徐州市消灭脊髓灰质炎策略实施效果良好。
Objective To understand the implementation of polio eradication strategy in Xuzhou from 2006 to 2009. Methods A total of 129 cases of AFP cases reported from 2006 to 2009 were collected from a case-control questionnaire and a follow-up table. Stool samples were collected from pre-vaccination and pre-vaccination serum samples and serum samples from 0 to 1 years old, 3 years old to 5 years old, Aged ~, 7 years old, 15 years old, 20 years old ~ Healthy people serum samples, respectively, virus isolation and antibody titer detection. Results The age of onset of 129 AFP cases was 14 years, the youngest was 83 days. There were 71 males and 58 females, accounting for 77.5% of the 11 cases. The incidence of non-polio AFP cases among children under 15 years of age from 2006 to 20009 was 2.33 per 100,000, 2.27 per 100,000, 1.92 per 100,000 and 1.67 per 100,000 respectively. The success rates of basic immunization of type I, II and III poliovaccine were 95.5%, 94.0% and 95.5%, respectively. The positive rates of type I, II and III neutralizing antibodies were 99.7%, 98.3% and 98.6%, respectively. Conclusion The strategy of polio eradication in Xuzhou is effective.