论文部分内容阅读
乙二醇醚及其醋酸酯在工业中应用广泛。已证实其主要代谢产物是烷氧基乙酸。作者认为,测定尿中排泄的甲氧基乙酸(MAA)与乙氧基乙酸(EAA)可以作为接触乙二醇醚的监测指标,并建立了相应的气相色谱测定方法。方法:尿样与标准液分析前加2～3滴5M氢氧化钾溶液,调至pH8～8.5,各取1ml,加入含50μg2—糠酸(β—呋喃甲酸,作为内标物)的水溶液100μl,然后进行冷冻干燥。向干燥残渣中加入10μl浓盐酸和1ml二氯甲烷,用
Glycol ethers and their esters are widely used in industry. It has been confirmed that its main metabolite is alkoxy acetic acid. The author believes that the determination of urine excretion of methoxy acetic acid (MAA) and ethoxy acetic acid (EAA) can be used as a monitoring indicator of contact glycol ethers, and the establishment of the corresponding gas chromatography. Method: Add 2 ~ 3 drops of 5M potassium hydroxide solution before the analysis of urine sample and standard solution, adjust to pH8 ~ 8.5, take 1ml each, add 100μl aqueous solution containing 50μg 2-furoic acid (β-furoic acid as internal standard) , Then freeze-dried. To the dry residue was added 10 μl of concentrated hydrochloric acid and 1 ml of methylene chloride