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目的探讨腹部肿瘤患者术后静脉应用混合糖溶液对其营养代谢指标的影响。方法选取腹部肿瘤且行根治术的成年患者56例,随机分为混合糖营养支持组和单糖营养支持组两组,术后3d禁食并分别持续静脉输注10.5%的混合糖溶液或10%的葡萄糖单糖溶液1000ml/d,测末梢血血糖并据此调整胰岛素用量,记录血糖、胰岛素情况且每天检测C反应蛋白(C-reactive protein,CRP)的水平。结果术后72h内,两组患者术后的血糖水平都较术前有所增高,在术后使用胰岛素情况下两组之间的血糖水平差异无统计学意义(P>0.05);混合糖组胰岛素用量显著低于单糖组(P<0.01);两组患者的CRP水平都较术前有所升高,单糖组较混合糖组升高更加明显(P<0.05)。结论腹部肿瘤根治术的患者,术后禁食并应用混合糖溶液作为糖源供能,机体血糖波动较小。此外,在减轻术后应激性炎症反应方面也起到了一定的作用。
Objective To investigate the effect of intravenous mixed sugar solution on the indices of nutritional metabolism in patients with abdominal tumor. Methods Fifty-six adult patients with abdominal tumor undergoing radical operation were randomly divided into two groups: mixed sugar nutrition support group and monosaccharide nutrition support group. After fasting for 3d and continuous intravenous infusion of 10.5% mixed sugar solution or 10% Of glucose monosaccharide solution 1000ml / d, measured peripheral blood glucose and adjust the amount of insulin accordingly, recording blood glucose, insulin and daily detection of C-reactive protein (C-reactive protein, CRP) levels. Results Within 72 hours after operation, the postoperative blood glucose levels in both groups were significantly higher than those before surgery. There was no significant difference in blood glucose levels between the two groups after insulin administration (P> 0.05) The dosage of insulin was significantly lower than that of monosaccharide group (P <0.01). The CRP level in both groups was higher than that in preoperative group. The monosaccharide group was more obvious than the mixed group (P <0.05). Conclusions Patients undergoing radical nephrectomy were fasted after operation and mixed with glucose solution as the source of glucose supply. The body blood glucose fluctuation was relatively small. In addition, it also plays a role in alleviating post-operative stress-induced inflammatory reaction.