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目的探讨中枢神经细胞瘤及脑室外神经细胞瘤的CT及磁共振成像(MR)特征。方法选取2014年9月至2015年3月四川省成都医学院第一附属医院收治的24例神经细胞瘤患者,按部位分为中枢神经细胞瘤(CNC)组和脑室外神经细胞瘤(EVN)组,CNC组15例,EVN组9例。两组患者均行CT、MRI以及病理学检查,分析其影像学和组织学的特点。结果 CT平扫显示,CNC组患者肿块呈稍高密度或等密度,边界清楚,肿瘤密度及囊变等情况因人而异。EVN组患者肿块边界不清,肿块密度及钙化、水肿及出血情况存在个体差异。MRI检查结果显示,CNC组患者T1WI以等信号或略低信号为主,T2WI呈等信号或高低混杂信号为主,肿瘤内部可见囊状的长T1、T2异常信号影,边缘可见血管流空信号。EVN组患者肿瘤以囊性为主,呈脑脊液样信号,少数实性部分呈稍长T1、T2异常信号。病理切片显示,CNC组患者肿瘤组织内细胞形态一致,呈流水样排列,肿瘤细胞内血管丰富,排列紧密。EVN组患者肿瘤组织与少突胶质细胞瘤组织相似,呈均匀一致的蜂窝状小细胞。结论 CNC的CT及MRI征象较典型,EVN常合并水肿和出血,CT和MRI对临床的诊断和鉴别诊断可提供依据。
Objective To investigate the CT and magnetic resonance imaging (MR) features of central neurocytoma and extracerebral neuroblastoma. Methods Twenty-four patients with neurocytoma admitted to the First Affiliated Hospital of Chengdu Medical College from September 2014 to March 2015 were divided into three groups: central neurocytoma (CNC) group and extracerebral neuroblastoma (EVN) Group, CNC group 15 cases, EVN group 9 cases. Two groups of patients underwent CT, MRI and pathological examination, analysis of its imaging and histological features. Results CT scan showed that the tumor mass in CNC group was slightly higher density or equal density, the boundary was clear, tumor density and cystic degeneration were different. EVN group of patients with unclear tumor lumps, lump density and calcification, edema and bleeding there are individual differences. The results of MRI showed that T1WI of CNC patients was mainly equal signal or slightly lower signal, T2WI was equal signal or mixed signal of high and low level, cystic T1, T2 abnormal signal inside the tumor was visible, . The tumors of EVN group were mainly cystic, showing cerebrospinal fluid-like signal. A few solid tumors showed slightly longer T1 and T2 abnormal signals. Pathological sections showed that the cells in the CNC group had the same cell morphology and flow-like arrangement, and the blood vessels in the tumor cells were abundant and closely arranged. The tumor tissue of EVN group was similar to that of oligodendroglioma, showing uniform and uniform cellular small cells. Conclusion The CT and MRI features of CNC are more typical. EVN is often associated with edema and hemorrhage. CT and MRI can provide the basis for clinical diagnosis and differential diagnosis.