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目的:研究转化生长因子-β(TGF-β)-Smad传导通路在病毒性心肌炎(VMC)慢性期心肌纤维化形成中的作用及三参饮治疗机制。方法:110只健康雄性Balb/c小鼠中的30只采用间断多次腹腔注射柯萨奇病毒B3(CVB3)的方法
Objective: To investigate the role of transforming growth factor-β (TGF-β) -Smad signaling pathway in the pathogenesis of chronic myocardical fibrosis in viral myocarditis (VMC) and its therapeutic mechanism. Methods: 30 out of 110 healthy male Balb / c mice were treated with intermittent multiple intraperitoneal injections of coxsackievirus B3 (CVB3)