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目的 评价术中超选择性动脉内置泵 ,术后区域灌注化疗对晚期胃肠道癌的疗效。方法 随访观察 79例手术证实不能切除的晚期胃肠道癌症患者 ,经超选择性动脉内置泵灌注化学药物的疗效。其中胃癌 42例 ,直肠癌 2 6例 ,结肠癌 11例。结果 化学药物治疗 (化疗 )后 ,完全缓解者 (CR) 1例 ;部分缓解者 (PR) 6 9例 ,其中 11例行二期根治性癌灶切除术。有效率 89%(70 / 79)。置泵术后生存满 1、2、3年者分别为 84%(6 6 / 79)、2 8%(2 2 / 79)、9%(7/ 79) ,平均生存期为 2 0 6个月。结论 术中超选择性动脉内置泵 ,术后泵内区域灌注化疗是治疗晚期胃肠道癌症的有效方法 ,可以延长患者的生存期 ,提高手术切除率。
Objective To evaluate the effect of intraoperative super selective arterial pump and postoperative regional perfusion chemotherapy on advanced gastrointestinal cancer. Methods The follow-up observation of 79 patients with advanced gastrointestinal cancer who were proved unresectable by surgery was performed. There were 42 cases of gastric cancer, 26 cases of rectal cancer and 11 cases of colon cancer. Results After chemotherapy (Chemotherapy), 1 patient had complete remission (CR) and 69 patients had partial response (PR). 11 patients underwent second-stage radical resection of the tumor. Efficiency 89% (70/79). The average survival time was 206% (28/79), 28% (2/79), 9% (7/79), and the average survival time was 20% month. Conclusions Intraoperative super selective arterial pump and regional intraperitoneal infusion pump are effective methods for the treatment of advanced gastrointestinal cancer. It can prolong the survival of patients and improve the surgical resection rate.