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目的探讨原发性卵巢平滑肌肉瘤的发生、诊断、鉴别、治疗及预后。方法分析我院1例原发性卵巢平滑肌肉瘤伴纤维瘤患者的临床病理资料,并复习相关文献。结果本文此例原发性卵巢平滑肌肉瘤伴纤维瘤患者未能早期诊断,肿瘤发展较快。确诊依靠病理并结合免疫组化Vimentin及SMA等。结论原发性卵巢平滑肌肉瘤早期发现较困难,预后差,放射线影像有助于诊断,手术后辅以适当的放疗及化疗,可能改善患者的预后。
Objective To investigate the occurrence, diagnosis, differentiation, treatment and prognosis of primary ovarian leiomyosarcoma. Methods A case of primary ovarian leiomyosarcoma with fibromatosis in our hospital clinical and pathological data, and review the relevant literature. Results In this case, the primary ovarian leiomyosarcoma patients with fibroids failed to diagnose early, the tumor developed rapidly. Diagnosis depends on the pathology combined with immunohistochemistry Vimentin and SMA. Conclusions Early detection of primary ovarian leiomyosarcoma is more difficult and the prognosis is poor. Radiographic imaging is helpful for the diagnosis. After surgery, the appropriate radiotherapy and chemotherapy may improve the prognosis of patients.