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与溶栓治疗相比,直接PTCA可恢复心外膜正常前向血流(TIMI-3),避免颅内出血,提高急性心肌梗死(AMI)患者的生存率。若在介入治疗前行适时早期药物再灌注(即所谓易化直接血管成形术),有可能进一步改善AMI患者的预后。这一理论如果成立,则在直接PTCA术前已经存在自发TIMI-3级血流的患者,预后应该比在PTCA术后血管才获得通畅的患者好。 方法 选择四项PAMI试验中连续2507例
Compared with thrombolytic therapy, direct PTCA can restore epicardial normal forward flow (TIMI-3), avoid intracranial hemorrhage, and improve survival in patients with acute myocardial infarction (AMI). Prolonged improvement of AMI patients’ prognosis may be possible if timely early drug reperfusion (so-called facilitated direct angioplasty) is performed prior to intervention. If this theory is validated, patients with spontaneous TIMI-3 grade prior to direct PTCA surgery should have a better prognosis than patients with patency after PTCA. Methods Select four consecutive PAMI test in 2507 cases