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目的评价天津市乙型病毒性肝炎相关疾病的间接疾病负担,为天津市制定乙型病毒性肝炎相关疾病防治策略及其策略的评价提供参考依据。方法采取多阶段整群抽样方法,对抽取的12个街或乡的547 782名居民进行调查,全面获取乙型病毒性肝炎、肝硬化和肝癌的现患、发病、死亡及失能等相关信息,采用简略公式计算失能调整寿命年(DALY)评价乙型病毒性肝炎相关疾病的间接疾病负担。结果 2010年天津市乙型病毒性肝炎相关疾病所造成的总间接疾病负担为63 041.1个DALYs,其中男性所致负担为39 113.9个DALYs,女性为23 927.1个DALYs;乙型病毒性肝炎、肝硬化和肝癌造成的间接疾病负担分别为5 786.3个DALYs、15 156.1个DALYs和42 098.7个DALYs;15岁以下年龄组的DALYs损失主要是乙型病毒性肝炎所致;45岁以上人群的DALYs损失主要由肝硬化和肝癌所致;由乙肝病毒感染造成的间接经济负担约为16.20亿元。结论乙型病毒性肝炎相关疾病造成的间接疾病负担非常严重,卫生部门应加大卫生资源投入的力度。
Objective To evaluate the indirect disease burden of hepatitis B-related diseases in Tianjin and provide reference for the prevention and control strategies of hepatitis B-related diseases in Tianjin. Methods A multistage cluster sampling method was used to investigate 547 782 residents of 12 townships or townships in the province and obtain comprehensive information on the prevalence, incidence, death and incapacity of hepatitis B, cirrhosis and liver cancer , A simplified formula was used to calculate the Indirect Disease Burden of Hepatitis B-related diseases in the Disability Adjusted Life Year (DALY). Results The total indirect disease burden caused by hepatitis B-related diseases in Tianjin was 63 041.1 DALYs in 2010, of which 39 113.9 DALYs were caused by males and 23 927.1 DALYs were females; hepatitis B, Indirect disease burden caused by cirrhosis and hepatocellular carcinoma were 5 786.3 DALYs, 15 156.1 DALYs and 42 098.7 DALYs, respectively. The loss of DALYs in the age group of 15 years and younger was mainly caused by hepatitis B. The loss of DALYs in people over 45 years old Mainly caused by cirrhosis and liver cancer; indirect economic burden caused by hepatitis B virus infection is about 1.620 billion yuan. Conclusion The burden of indirect disease caused by hepatitis B-related diseases is very serious, and the health department should increase the investment of health resources.