一百年前,人们就发现体温增高可以使某些肿瘤消退,并用高温来治疗肿瘤,60年代,由于放疗的发展,高温治疗曾一度被放疗所取代,70年代又重新被人们所重视。目前治疗恶性肿瘤的高温技术很多,如加热液灌注法、透热和微波加温、液体浸渍和冲洗、低频 RF 电场、超声波等。我们采用恒温流水热敷法,治疗小鼠移植性肿瘤,目的 One hundred years ago, people discovered that an increase in body temperature could cause certain tumors to subside and treat tumors with high temperatures. In the 1960s, due to the development of radiotherapy, hyperthermia treatment was once replaced by radiation therapy, and in the 1970s it was re-emphasized. At present, there are many high-temperature techniques for treating malignant tumors, such as heating liquid perfusion method, diathermy and microwave heating, liquid dipping and rinsing, low-frequency RF electric fields, and ultrasonic waves. We use a constant temperature water-heating method to treat transplanted tumors in mice.