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目的:探讨微波固化治疗口腔癌的临床价值。方法:回顾性分析中山医科大学肿瘤防治中心头颈科1989年10月1日～1998年5月30日经微波固化方法治疗的96例口腔癌病例(舌癌和口底癌),比较其生存率、复发率、并发症和口腔功能状况。结果:本组的5年生存率是581%,Ⅰ期、Ⅱ期、Ⅲ期和Ⅳ期5年生存率分别是763%、688%、514%和191%(LogRank=2688,P=00000);原发灶复发率是135%;颈淋巴结转移率是167%;出现微波固化治疗的特有并发症共9例。舌癌病例中,无口底侵犯者口腔功能良好、口腔功能一般和口腔功能差者分别占833%、167%和0%;有口底侵犯的舌癌病例和口底癌病例口腔功能良好、一般和差者分别占574%、278%和148%。结论:微波固化治疗口腔癌具有提高生存率、较好的局部区域控制率,以及并发症少和保全口腔功能好的特点,是安全有效的治疗方法。
Objective: To explore the clinical value of microwave curing for oral cancer. METHODS: Retrospective analysis was performed on 96 cases of oral cancer (tongue cancer and floor cancer) treated by microwave curing at the Head and Neck Department of Cancer Center of Sun Yat-sen University of Medical Sciences from October 1, 1989 to May 30, 1998. The survival rate was compared. , recurrence rate, complications and oral functional status. Results: The 5-year survival rate was 581% in this group. The 5-year survival rates for phase I, II, III, and IV were 763%, 688%, 514%, and 191%, respectively (LogRank=2688, P=00000). The recurrence rate of the primary tumor was 135%; the rate of cervical lymph node metastasis was 167%; there were 9 cases of special complications of microwave curing therapy. Among the tongue cancer cases, those with no oral floor aggressors had good oral function, normal oral function, and poor oral function, accounting for 833%, 167%, and 0%, respectively; tongue cancers with oral floor invasion and oral cavity cancer cases had good oral function. The average and the poor accounted for 574%, 278% and 148% respectively. Conclusion: Microwave curing treatment of oral cancer has the advantages of improving survival rate, better regional control rate, less complications and preservation of oral function. It is a safe and effective treatment method.