大量的研究表明口腔感染与动脉粥样硬化的发生和发展有关。其相关机制主要包括细菌直接侵入血管内皮,损害血管内皮细胞,引起C反应蛋白(CRP)升高,促进炎症细胞因子释放和表达,促进血小板聚集以及通过自身免疫反应和炎症反应影响血管壁来促进动脉粥样硬化的发生。本文就近年来该领域的研究现状作一综述。 A large number of studies have shown that oral infections and the occurrence and development of atherosclerosis. The mechanisms involved include direct bacterial invasion into the vascular endothelium, vascular endothelial cells, causing increased C-reactive protein (CRP), promoting the release and expression of inflammatory cytokines, and promoting platelet aggregation as well as by autoimmune and inflammatory reactions affecting the vascular wall to promote Atherosclerosis occurs. This article summarizes the research status in this field in recent years.