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作者报道了新英格兰滋养细胞疾病研究中心自1975年1月～1980年5月,随机抽样观察了100例葡萄胎,在葡萄胎清除后,使用口服避孕药是否会增加滋养叶肿瘤的发病率。在100例中葡萄胎清除后立即服用避孕药者58例(58%),年龄17～33岁,平均为23.6岁。应用泡沫、阴茎套、阴道隔膜避孕者42例(42%),年龄15～49岁。平均为25.9岁。妊娠次数:服避孕药组为1～5次,其中26例(44.8%)为第一次妊娠。用阴茎套避孕为1～5次,17例(40.5%)为第一次妊娠。作者对每个病人的葡萄胎组织均作了病理分级(按Hertig和
The authors report that from January 1975 to May 1980, the New England Trophoblastic Disease Research Center observed 100 random hydatidiform mole fetuses and whether oral contraceptives increased the incidence of trophoblastic tumors after hydatidiform mole removal. 58 cases (58%) of contraceptive pills were taken immediately after cleansing in 100 cases, aged from 17 to 33 years with an average of 23.6 years old. Application of foam, condoms, vaginal diaphragm contraception in 42 cases (42%), aged 15 to 49 years. The average is 25.9 years old. The number of pregnancy: taking contraceptives for 1 to 5 times, of which 26 cases (44.8%) for the first pregnancy. Contraception with a condom 1 to 5 times, 17 cases (40.5%) for the first pregnancy. The author of each patient’s hydatidiform mole histopathological grading (according to Hertig and