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目的:探讨多西环素联合盆腔炎2号方治疗支原体感染盆腔炎疗效及安全性分析。方法:选择2015年1月—2016年6月期间于医院就诊收治的支原体感染盆腔炎患者80例为研究对象,根据随机数字表法将两组患者均分为观察组与对照组各40例,其中对照组患者单独给予多西环素治疗,观察组患者在对照组的基础上联合应用盆腔炎2号方治疗,常规治疗后比较两组患者的临床治疗效果、治疗期间的不良反应情况以及患者子宫血流动力学指标指标之间的差异情况。结果:两组患者治疗后,其中观察组患者的临床治愈患者例数27例、治愈率67.5%,明显的高于对照组患者的19例、47.5%,两组比较差异有统计学意义(P<0.05),可以比较;观察组患者的临床治疗无效例数1例、无效率2.5%,明显的低于对照组患者的6例、15.0%,两组比较差异有统计学意义(P<0.05),可以比较;观察组患者治疗期间头晕头痛患者2例、恶心呕吐2例、腹泻0例、肝功能异常1例,明显的低于对照组患者的头晕头痛患者5例、恶心呕吐4例、腹泻5例、肝功能异常3例,两组比较差异有统计学意义(P<0.05),可以比较;观察组患者的阻力指数(RI)0.86±0.03、搏动指数(PI)2.49±0.09以及平均血流速度(Vmin)0.60±0.03,明显的高于对照组患者的阻力指数(RI)0.80±0.02、搏动指数(PI)2.20±0.06以及平均血流速度(Vmin)0.41±0.02,两组比较差异有统计学意义(P<0.05),可以比较。结论:多西环素联合盆腔炎2号方在支原体感染盆腔炎的临床治疗过程中,具有较好的临床治疗效果以及安全性,治疗期间的药物不良反应情况发生率低,可以有效地改善患者的血流动力学指标,在临床上具有极高应用价值,值得进一步推广使用。
Objective: To investigate the efficacy and safety of doxycycline combined with pelvic inflammatory disease in the treatment of pelvic inflammatory disease. Methods: From January 2015 to June 2016, 80 patients with mycoplasma-infected pelvic inflammatory disease admitted to the hospital were selected as the research objects. According to the random number table, the two groups were divided into observation group and control group, 40 cases each. The control group of patients given alone doxycycline treatment, the observation group patients in the control group based on the combination of pelvic inflammatory disease on the 2nd treatment, routine treatment, the clinical efficacy of the two groups were compared, the adverse reactions during treatment and patients Uterine hemodynamic indicators of the differences between the indicators. Results: After treatment, the number of clinical cure patients in the observation group was 27, the cure rate was 67.5%, significantly higher than that in the control group (19.57% and 47.5%, P <0.05), and there was significant difference between the two groups <0.05). One case of ineffective clinical treatment and 2.5% ineffective clinical observation in observation group were significantly lower than 6 cases in control group (15.0%), the difference between the two groups was statistically significant (P <0.05 ), Can be compared; observation group 2 patients with dizziness and headache during treatment, nausea and vomiting in 2 cases, 0 cases of diarrhea, liver dysfunction in 1 case, significantly lower than the control group of patients with dizziness and headache in 5 cases, nausea and vomiting in 4 cases, (RI) 0.86 ± 0.03, pulsatility index (PI) 2.49 ± 0.09, mean (P <0.05), and the mean The blood flow velocity (Vmin) was 0.60 ± 0.03, significantly higher than that of the control group (RI 0.80 ± 0.02, pulsatility index (PI) 2.20 ± 0.06 and mean blood flow velocity (Vmin) 0.41 ± 0.02) The difference was statistically significant (P <0.05), can be compared. Conclusion: The combination of doxycycline and pelvic inflammatory disease in the treatment of pelvic inflammatory disease in patients with mycoplasma infection has good clinical efficacy and safety, the incidence of adverse drug reactions during treatment is low, which can effectively improve the patients Hemodynamic indicators, has a very high clinical value, it is worth to further promote the use of.