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目的对职业性三硝基甲苯(TNT)白内障患者治疗前后眼部血流动力学改变进行分析,了解其治疗效果。方法对广西壮族自治区职业病防治研究院2010—2012年期间收治45例职业性TNT白内障患者的临床资料进行回顾性的分析,采用黄芪注射液联合还原型谷胱甘肽滴眼液对45例患者实施治疗,B超检查眼动脉、视网膜中央动脉血流改变情况,比较、分析治疗前、后的眼部血流动力学情况。结果经过一段的时间的治疗以后,45例职业性TNT白内障患者眼部的眼动脉收缩期的平均血流速度、眼动脉舒张期的平均血流速度、视网膜中央动脉收缩期的平均血流速度、视网膜中央动脉舒张期的平均血流速度与治疗前比较都有提高,其中眼动脉和视网膜中央动脉收缩期血流速度与治疗前比较差异具有统计学意义(P<0.05)。结论职业性TNT白内障患者,其眼部周围的血液循环存在供血不足的问题,采用黄芪注射液联合还原型谷胱甘肽滴眼液的治疗方法来扩张眼部血管、增加眼部血流量,对于改善TNT白内障患者眼部的血流动力、促进其视力恢复具有积极意义。
Objective To analyze the ocular hemodynamic changes of occupational TNT cataract patients before and after treatment to find out the therapeutic effect. Methods The clinical data of 45 cases of occupational TNT cataract treated in Guangxi Zhuang Autonomous Region Occupational Disease Prevention and Treatment Institute from 2010 to 2012 were retrospectively analyzed. Forty-five patients were treated with Astragalus injection combined with reduced glutathione eye drops Treatment, B ultrasound examination of the ophthalmic artery, central retinal artery blood flow changes, compared and analyzed before and after treatment of ocular hemodynamics. Results After a period of treatment, the ophthalmic arterial systolic mean flow velocity, mean arterial diastolic blood flow velocity, central retinal artery systolic blood flow velocity, The average velocity of diastolic blood flow of the central retinal artery increased compared with that before treatment. The systolic velocity of the central artery of the ophthalmic artery and the retina was significantly different from that before treatment (P <0.05). Conclusion Occupational TNT cataract patients, the blood circulation around the eye there is the problem of insufficient blood supply, the use of Astragalus injection combined with reduced glutathione eye drops to expand the treatment of ocular blood vessels and increase eye blood flow, for It is of positive significance to improve the hemodynamics of eye in TNT cataract patients and promote their visual acuity recovery.