论文部分内容阅读
目的:观察乳康灵抗乳腺增生作用及对乳腺增生大鼠血清性激素水平的影响。方法:应用苯甲酸雌二醇、黄体酮建立乳腺增生大鼠模型,不同剂量乳康灵方作用于乳腺增生大鼠,检测药物作用后乳房直径、乳头高度,卵巢、子宫脏器系数及血清性激素含量。结果:乳康灵方明显减小乳房直径和乳头高度,降低卵巢脏器系数,明显降低血清雌二醇、催乳素水平,但对孕酮水平无明显影响。结论:乳康灵方能抑制雌激素异常致乳房肿大,改善血清性激素水平紊乱,具有抗乳腺增生作用。
OBJECTIVE: To observe the effect of Runkangling on breast hyperplasia and its effect on serum sex hormone levels in mammary gland hyperplasia rats. Methods: Breast hyperplasia rat models were established by using estradiol benzoate and progesterone. Different doses of Rukanglingfang were used in rats with hyperplasia of mammary glands. The diameters of the breast, the height of the nipple, the organ coefficients of ovary, uterus and serum sex hormone content. Results: Rukanglingfang significantly reduced breast diameter and nipple height, decreased ovarian organ coefficient, decreased serum estradiol and prolactin levels, but had no significant effect on progesterone levels. Conclusion: Rukangling Decoction can inhibit estrogen induced breast enlargement, improve the level of serum sex hormone disorders, with anti-breast hyperplasia.