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随着冠状动脉粥样硬化性心脏病在全球范围内发病率的日益增高,其所带来的高病死率和高致残率在消耗国家公共资源的同时也阻碍着人们生活质量的提高。面对这一严峻局面,全球科学家都积极致力于其发病机制的研究,从宏观因素到分子水平,以期找到预防和治疗的新方法。随着人类基因组草图绘制的完成为大家开展基因研究提供了更加方便、快捷的平台,大家的目光也更多的聚集于糖尿病、冠状动脉粥样硬化性心脏病等常见多基因复杂疾病基因层面的研究。在这样的大背景下,针对冠状动脉粥样硬化性心脏病易感基因开展的研究亦取得了不俗进展。
With the increasing global incidence of coronary atherosclerotic heart disease, its high mortality and morbidity will hinder the improvement of people’s quality of life while consuming national public resources. In the face of this grim situation, scientists all over the world are actively committed to the study of their pathogenesis, from macroscopic to molecular level, with a view to finding new ways of prevention and treatment. With the completion of the human genome sketching completed for everyone to carry out gene research provides a more convenient and efficient platform, everyone’s eyes are more gathered in diabetes, coronary heart disease and other common multi-gene complex disease gene level the study. In this context, research on susceptibility genes for coronary atherosclerotic heart disease has also made good progress.