【摘 要】
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Childhood maltreatment (CM) has been consistently linked with numerous detrimental outcomes concerning physical and psychological health.However,few studies have explored vulnerability to neurological disorders after CM.Early life adversity,in the form of
【机 构】
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Division of Experimental Neuroscience,I RCCS Santa Lucia Foundation,Rome,Italy;Division of Experimen
论文部分内容阅读
Childhood maltreatment (CM) has been consistently linked with numerous detrimental outcomes concerning physical and psychological health.However,few studies have explored vulnerability to neurological disorders after CM.Early life adversity,in the form of poverty,stress and abuse,has been associated with decline in cognitive function and dementia later in life(Short and Baram,2019).Robust preclinical data suggest that early life stress (ELS) may increase the risk and worsen the course of neurological disorders such as Alzheimer\'s (AD)and Parkinson\'s (PD) diseases,and traumatic brain injury (TBI) (Lesuis et al.,2018;Short and Baram,2019;He et al.,2020;Catale et al.,2021;Sanchez et al.,2021).
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