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目的了解云南省与缅甸接壤边境地区儿童脊髓灰质炎(脊灰)中和抗体(Neutralizing Antibody,NA)水平。方法采用单纯随机抽样的方法,在保山市、德宏傣族景颇族自治州和临沧市,随机抽取到医院门诊就诊或体检的<15岁儿童进行调查,每个设区的市(州)调查150人,分5个年龄组每个年龄组调查30人,检测脊灰NA。结果脊灰NAI、II、III型阳性率分别为95.11%、97.56%、94.67%,几何平均滴度(Geometric Mean Titers,GMT)分别为1∶90.65,1∶65.31,1∶57.86。随着年龄增长,NAGMT呈现下降趋势,II型和III型NAGMT下降趋势明显。结论云南省与缅甸接壤边境地区<15岁儿童保持较高的NA水平,NAGMT随年龄增长而逐步下降,需保持高的脊灰疫苗接种率,适时采取补充免疫措施。
Objective To understand the level of Neutralizing Antibody (NA) in children bordering Yunnan Province and Myanmar. Methods A simple random sampling method was used to survey 15-year-old children from outpatient clinics or physical examinations in Baoshan, Dehong Dai-Jingpo Autonomous Prefecture and Lincang. People, divided into five age groups of 30 people in each age group, detection of polio NA. Results The positive rates of NAI, II and III of pollens were 95.11%, 97.56% and 94.67%, respectively. The Geometric Mean Titers (GMT) were 1:90.65, 1:65.31 and 1:57.86, respectively. With age, NAGMT showed a downward trend, type II and III NAGMT decreased significantly. Conclusion The NA level of 15-year-old children in border areas between Yunnan and Myanmar is relatively high. The NAGMT decreases gradually with age. It is necessary to maintain a high polio vaccination rate and to take supplementary immunization measures in time.