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本文检测进展期和手术１个月后肝癌、胃癌、大肠癌、乳腺癌患者外周血白细胞介素－２（ＩＬ－２）、白细胞介素－６（ＩＬ－６）活性及可溶性白细胞介素－２受体（ＩＬ－２Ｒ）的水平。结果表明：①各组进展期癌症患者外周血ＩＬ－２、ＩＬ－６活性均显著低于对照组，而ＩＬ－２Ｒ水平却均显著高于对照组。各组癌症之间上述各项指标比较均无明显差异。②手术后１个月时各组癌症患者外周血ＩＬ－２、ＩＬ－６活性有所恢复，ＩＬ－２Ｒ水平有所下降，但仍低于正常人群。结果提示，癌症患者外周血Ｔ细胞功能被严重抑制，这种变化与疾病的病情发展和治疗有关。
This study examined the activity of peripheral blood interleukin-2 (IL-2), interleukin-6 (IL-6) and soluble interleukin in patients with advanced hepatocellular carcinoma, gastric cancer, colorectal cancer, and breast cancer 1 month after surgery. 2 receptor (IL-2R) levels. The results showed that: 1 The activity of IL-2 and IL-6 in the peripheral blood of patients with advanced cancer was significantly lower than that of the control group, while the IL-2R level was significantly higher than that of the control group. There was no significant difference in the above indicators between the groups of cancers. 2 At 1 month after surgery, the activity of IL-2 and IL-6 in peripheral blood of various groups of cancer patients recovered, IL-2R levels decreased, but it was still lower than the normal population. The results suggest that peripheral blood T cell function is severely inhibited in cancer patients, and this change is related to disease progression and treatment.