1983年11月开始,北京、吉林两市先后发现手足口病病人,至1984年3～4月达流行高峰。作者对此进行了全面观察研究,除流行病学和临床资料等另文发表外,本文报道在部分病人中检测疱疹液、咽拭子、粪便和双份血标本的初步结果。 29名北京地区病人作病毒学和/或血清学检查证实,18人(62.01％)为柯萨奇A16病毒(CoxA16)感染。其中2人从疱疹液分离出CoxA16;3人咽拭子或粪便分离到病毒同时双份血清示抗CoxA Beginning in November 1983, Beijing and Jilin cities successively discovered hand-foot-mouth disease patients and reached the peak of popularity from March to April 1984. The authors conducted a comprehensive observational study, in addition to other published epidemiological and clinical data, this article reports the detection of herpes fluid in some patients, throat swabs, stool and blood samples of the two preliminary results. Virology and / or serological tests on 29 patients in Beijing confirmed that 18 (62.01%) were CoxA16-infected. Two of them isolated CoxA16 from the herpes fluid; the throat swab or feces of 3 people separated the virus and the duplicate serum showed anti-CoxA