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慢性支气管肺疾病和粘稠物阻塞症(MS)是现代小儿肺病学家的重要问题,但对本病发生止血障碍却研究很少。作者观察127例1～15岁小儿,其中84例为慢性肺炎(原发46例,继发22例),43例为MS。MS 状态严重者17例,中度20例,轻度6例。18例表现慢性肺心病征象,4例有胆汁性肝硬化,9例有慢性肝炎。全部MS 患儿入院时均处于极期,慢性肺炎患儿中仅18例入院时为缓解期,其余为极期。血凝固性试验检查结果表明,全部患儿显示血凝固性增高,最高者为MS 组。有15%MS,4.5%复发性慢性肺炎患儿疾病严重伴有低凝状态。表现为鼻衄,注射和插导管部位出血,肺出血(1例)。血纤维蛋白原含量在全部患儿极期和缓解期均降低(P<0.01),仅有1例增高为继发性慢性肺炎伴肺出血症状。
Chronic bronchopulmonary disease and visceral obstruction (MS) are important problems for modern pediatric pulmonary physicians, but little is known about the hemostatic disorders of this disease. The authors observed 127 children aged 1 to 15 years, of whom 84 were chronic pneumonia (primary 46, secondary 22) and 43 were MS. 17 cases of severe MS, moderate in 20 cases, mild in 6 cases. 18 cases showed signs of chronic pulmonary heart disease, 4 cases of biliary cirrhosis, 9 cases of chronic hepatitis. All MS children admitted to the hospital at a very early stage, only 18 children with chronic pneumonia admission remission, the rest is extremely. Blood coagulation test results showed that all children showed increased blood coagulation, the highest for the MS group. 15% of MS, 4.5% of children with recurrent chronic pneumonia, severe disease associated with low coagulation status. The performance of epistaxis, injection and insertion of catheter bleeding, pulmonary hemorrhage (1 case). The content of fibrinogen was decreased in both extreme and remission stages of all children (P <0.01), while only one of them was elevated to secondary chronic pneumonia with pulmonary hemorrhage.